Breast Cancer Personalized Medicine
نویسندگان
چکیده
منابع مشابه
Breast Cancer Personalized Medicine
W.B.C. is Special Editor of the Breast Cancer Theme Issue. Personalized medicine, individualized medicine, and precision medicine are interchangeable terms that describe an approach to the treatment of disease that harnesses our understanding of the molecular basis and mechanisms of a given disease and matches appropriate therapeutic interventions. Breast cancer represents a diverse collection ...
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Despite diagnostic, preventive and therapeutic advances, growing incidence of cancer and high rate of mortality among patients affected by specific cancer types indicate current clinical measures are not ideally useful in eradicating cancer. Chemoresistance and subsequent disease relapse are believed to be mainly driven by the cell-molecular heterogeneity of human tumors that necessitates perso...
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Breast cancer is a complex disease caused by the progressive accumulation of multiple gene mutations combined with epigenetic dysregulation of critical genes and protein pathways. There is substantial interindividual variability in both the age at diagnosis and phenotypic expression of the disease. With an estimated 1,152,161 new breast cancer cases diagnosed worldwide per year, cancer control ...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 2013
ISSN: 0002-9440
DOI: 10.1016/j.ajpath.2013.08.001